About Us

Invibragen focuses on enabling high-throughput molecular analysis and advancing cutting-edge research in ionization sensitivity, ion source utility, and emerging analytical applications. The company's Spanda platform is backed by peer-reviewed research and supported by federal research funding, including multiple awards from the U.S. National Science Foundation and National Institutes of Health.

Invibragen is led by Professor Stephen Valentine and Professor Peng Li, experts in bioanalytical chemistry and instrumentation, together with a multidisciplinary team working at the intersection of analytical chemistry, mass spectrometry, and applied research.


SELECTED PUBLICATIONS

Peer-Reviewed Research Highlights

Scientific Publications Slider
ACS PHYSICAL CHEMISTRY AU • 2024

Structure Characterization of a Disordered Peptide Using In-Droplet Hydrogen/Deuterium Exchange Mass Spectrometry and Molecular Dynamics

Open publication
ELECTROPHORESIS • 2024

Protein Analysis Using Capillary Electrophoresis Coupled to Mass Spectrometry Through Vibrating Sharp-Edge Spray Ionization

Open publication
ANALYTICAL CHEMISTRY • 2022

Development of cVSSI-APCI for the Improvement of Ion Suppression and Matrix Effects in Complex Mixtures

Open publication
ANALYTICAL CHEMISTRY • 2022

Nanoflow Sheath Voltage-Free Interfacing of Capillary Electrophoresis and Mass Spectrometry for the Detection of Small Molecules

Open publication
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY • 2021

Combining Field-Enabled Capillary Vibrating Sharp-Edge Spray Ionization with Microflow Liquid Chromatography and Mass Spectrometry to Enhance ‘Omics Analyses

Open publication
ANALYTICAL CHEMISTRY • 2020

Facile Improvement of Negative Ion Mode Electrospray Ionization Using Capillary Vibrating Sharp-Edge Spray Ionization

Open publication
RAPID COMMUNICATIONS IN MASS SPECTROMETRY • 2020

Direct Analysis of Surface Chemicals Using Vibrating Sharp-Edge Spray Ionization Mass Spectrometry

Open publication
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY • 2019

Capillary Vibrating Sharp-Edge Spray Ionization (cVSSI) for Voltage-Free Liquid Chromatography-Mass Spectrometry

Open publication

Our journey has been anything but ordinary. Through every step, we've focused on staying true to our values and making space for thoughtful, lasting work.

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Let’s Work Together

What began as a passion project has evolved into something more. We’re proud of where we’ve been and even more excited for what’s ahead.

What sets us apart isn’t just our process—it’s the intention behind it. We take time to understand, explore, and create with purpose at every turn.